09 abril, 2008

Cancer's Cosa Nostra

Us copio un petit fragment d'un article publicat a Science aquest mes sota el títol "All in the Stroma: Cancer's Cosa Nostra", que resum molt bé la direcció que pren la meva recerca després de la tesi.

As several spectacular cases have shown, corporate criminals can operate for years, bending office systems to their nefarious deeds. Eventually, the malfeasance can threaten the entire company. So it is with cancer cells. Cancer biologists have recently been coming to grips with the fact that tumor cells get a lot of help from the cells around them. Such collusion is not the source of disease: More than 30 years of research have shown that mutations in a cell's own DNA initiate the changes that put it on its destructive path. But "people are realizing that the tumor environment is a coconspirator," says Zena Werb of the University of California, San Francisco (UCSF). "There's benn a clear shift in interest". - J Marx.

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